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Monday, April 27, 2020 | History

2 edition of Occupational exposure to cresol found in the catalog.

Occupational exposure to cresol

National Institute for Occupational Safety and Health. Division of Criteria Documentation and Standards Development

Occupational exposure to cresol

criteria for a recommended standard

by National Institute for Occupational Safety and Health. Division of Criteria Documentation and Standards Development

  • 289 Want to read
  • 30 Currently reading

Published by U.S. Dept. of Health, Education and Welfare, Public Health Service, Center for Disease Control, National Institute for Occupational Safety and Health, for sale by the Supt. of Docs., U.S. Govt. Print. Off. in [Cincinnati, Ohio, Washington, D.C .
Written in English

    Subjects:
  • Cresol -- Physiological effect,
  • Cresol -- Toxicology,
  • Industrial hygiene -- Standards -- United States,
  • Industrial safety -- Standards -- United States

  • Edition Notes

    Other titlesCriteria for a recommended standard, occupational exposure to cresol, NIOSH criteria for a recommended standard, occupational exposure to cresol
    Statement[Division of Criteria Documentation and Standards Development, National Institute for Occupational Safety and Health].
    SeriesDHEW publication -- no. (NIOSH) 78-133
    ContributionsS.R.I. International
    Classifications
    LC ClassificationsRC963.3 N383365
    The Physical Object
    Paginationx, 117 p. :
    Number of Pages117
    ID Numbers
    Open LibraryOL22261936M

    to substantial occupational exposure The ITC cited the National Institute for Occupational Safety and Healths (NIOSH) estimates that roughly 2 million workers are exposed to cresols. The ITC also was concerned that cresols are used in many consumer products and that these uses couldresult in a large consumer and general population exposure. C.   Non-occupational chloracne has resulted from industrial accidents, contaminated industrial waste, and contaminated food products. A widely publicized example was the extensive environmental contamination with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (Fig. 1), which occurred on J , at the ICMESA chemical plant near Seveso, Italy Cited by:


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Occupational exposure to cresol by National Institute for Occupational Safety and Health. Division of Criteria Documentation and Standards Development Download PDF EPUB FB2

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Occupational exposure to cresol. [National Institute for Occupational Safety and Health.] Print book: National government publication: EnglishView all editions and formats: Rating: National Institute for Occupational Safety and Health.

Occupational exposure to cresol. [Rockville, Md.]: Dept. of Health, Education, and Welfare, Public. Links with this icon indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.

Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.

Employers must comply with a number of standards where employees are potentially exposed to chemical hazards. These include OSHA's Permissible Exposure Limits PELs for about substances, which can be found as follows: General Industry: 29 CFRToxic and Hazardous Substances.

Air contaminants and Z1, Z2, Z3 tables. Occupational exposure to dinitro-ortho-cresol. [National Institute for Occupational Safety and Health.] Print book: National government publication: EnglishView all editions and formats: Education, and Welfare, Public Health Service, Center for Disease Control, National Institute for Occupational Safety and Health\/span>\n \u00A0.

"Criteria for recommended standard occupational exposure to cresol () have been established and are presented. Criteria and recommendations for cresol apply to the o, m, p, isomers or to any combination of the three isomers in a mixture.

In addi. M-cresol is a cresol with the methyl substituent at position 3. It is a minor urinary metabolite of toluene. It has a role as a human xenobiotic metabolite. M-cresol is a colorless liquid with a sweet tarry odor.

Sinks and mixes slowly with water. (USCG, ) from CAMEO Chemicals. from Human Metabolome Database (HMDB) Expand this section.

Recommendation of Occupational Exposure Limits (–) The Japan Society for Occupational Health May, 17, The Japan Society for Occupational Health (JSOH) recommends the Occupational Exposure Limits (OELs) File Size: 1MB. Structure and production. In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol.

There are three forms of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol).These forms occur separately or as a mixture, which can also be called cresol or more specifically, tricresol.

[citation needed] About half of the. o-Cresol is a minor urinary metabolite of toluene, a widely used chemical with neurotoxicological properties.(PMID: ). o-Cresol is used commercially as a re may occur by inhalation, by cutaneous adsorption or by oral ingestion. o-Cresol denature and precipitate cellular proteins and thus may rapidly cause poisoning.

o-Cresol is metabolized by. Occupational chronic exposure to organic solvents. XII. O-cresol excretion after toluene exposure. Angerer J. Thirty-five printing workers were investigated according to their external and internal exposure to toluene. The concentration of toluene in the air of the working place was determined using stationary air sampling and gas by:   Thirty-five printing workers were investigated according to their external and internal exposure to toluene.

The concentration of toluene in the air of the working place was determined using stationary air sampling and gas chromatography. To determine the levels of toluene in blood as well as the concentrations of o-cresol, hippuric acid, and phenol in urine, Cited by: Permissible Exposure Limits / OSHA Annotated Table Z-1; Note: This table only includes occupational exposure limits (OELs) for substances listed in the OSHA Z-1 Table.

OELs for hundreds of additional substances have been adopted by Cal/OSHA, NIOSH, and organizations periodically make revisions to their OELs and so they should be consulted. Andersson R, Carlsson A, Nordqvist MB, Sollenberg J.

Urinary excretion of hippuric acid and o-cresol after laboratory exposure of humans to toluene. Int Arch Occup Environ Health. ; 53 (2)– Angerer J. Occupational chronic exposure to organic solvents. VII. Metabolism of toluene in man. Int Arch Occup Environ by: Measurement of tremor has been used in several occupational studies of workers with long-term exposure to mercury vapor (Hg(0)).

Recent studies indicate an. Occupational exposure to mixed cresols may also occur at workplaces where mixed cresols and/or cresol containing products are produced or used.

(1) Assessing Personal Exposure Mixed cresols can be measured in the urine of exposed individuals. Health Hazard Information.

11 Angerer J. Occupational chronic exposure to organic solvents XII. o-cresol excretion after toluene exposure. IntArchOccupEnvironHealth ; 12 Nise G. Urinary excretion of o-cresol and hippuric acid after toluene exposure in rotogravure printing. IntArch OccupEnvironHealth ; 13 SedivecV, FlekJ.

Theabsorption Cited by: Comparison of hippuric acid, and o-cresol in urine and unchanged toluene in alveolar air for the biological monitoring of exposure to toluene in human volunteers. Tardif R., Truchon G., Brodeur J. Source: Applied Occupational and Environmental Hygiene, vol.

13, no 2,p. O-Cresol: A good indicator of exposure to low levels of toluene. Occupational Exposure To Chemicals: HazMap was retired. The content of Haz-Map is still provided by the original content provider: Risk Assessment: TOXNET's IRIS was retired. Visit IRIS at EPA. Comparison of hippuric acid, and o-cresol in urine and unchanged toluene in alveolar air for the biological monitoring of exposure to toluene in human volunteers.

Tardif R., Truchon G., Brodeur J. Source: Applied Occupational and Environmental Hygiene, vol. 13, no 2,p. O-Cresol: A good indicator of exposure to low levels of toluene. p-Cresol oral LD 50 mg/kg in mice; dermal LD 50 mg/kg in rats; subcutaneous LD 50 mg/kg in mice, mg/kg in guinea pigs.

Exposure can cause irritation to the eyes, nose and throat, severe eye damage, vomiting, sleeplessness and damage to the lungs, liver, kidneys, blood, nervous system and respiratory system. Ortho-Cresol as Indicator for Toluene Exposure among Workers. Abd. Rahim Yacob. 1 and Nazirah Said.

1,2. Chemistry Department, Faculty of Science, Universiti Teknologi Malaysia,Johor Bahru, Johor, Malaysia. Abstract. Toluene is a volatile organic solvent used by most industries and. household items such as. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here.

Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties.

Other pertinent literature is also presented, but is described in less. Cresols are a widely occurring natural and manufactured group of chemicals.

In their pure form, they are colorless solids and may be liquids if they are mixtures. Cresols smell like medicine. There are three forms of cresols that differ slightly in their chemical structure: ortho-cresol (o-cresol), meta-cresol (m-cresol, and para-cresol (p-cresol).

m-Cresol Revision Date Jan Viscosity No information available Molecular Formula C7 H8 O Molecular Weight Stability and reactivity Reactive Hazard None known, based on information available Stability Stable under normal conditions.

Light sensitive. Conditions to Avoid Incompatible products. Exposure to light. Occupational exposure to airborne substances harmful to health: ILO: ILO: Occupational exposure to airborne substances harmful to health: Dr A. Rothan: ILO: Occupational exposure to acrylamide: NIOSH: NIOSH: Occupational exposure to 1,1,1,- tri chloro ethane (methyl) c: NIOSH: NIOSH.

At the time, the concentration of o-cresol was about two and half times and that of p-cresol was one and half times larger than pre-exposure values. These substances were related to toluene inhalation and the values of the biological half time of o- Cited by: 7.

Occupational Exposure Limits m-cresol purple (Particles (Insoluble or Poorly Soluble) [NOS] Inhalable particles) 10 See Appendix B current TLV/BEI Book ENDOELTABLE PERSONAL PROTECTION RESPIRATOR Particulate Consult your EHS staff for recommendations EYE Safety glasses with side shields.

Description and Properties, - A colorless or straw-colored refractive liquid having a phenol-like odor and turning yellowish-brown on prolonged exposure to light. Sometimes erroneously called crecylic acid. Cresol is methyl phenol, the three isomeric forms being known chemically as ortho- meta- and paracresol.

the potential for occupational and consumer exposure and the lack of chronic toxicity data. Male F/N rats and female B6C3F1 mice were exposed to a mix-ture of m‑ and p‑cresol (m‑/p‑cresol) (greater than % pure) in feed for 2 years.

Genetic toxicology studies were conducted in Salmonella typhimurium, Escherichia. p-Cresol >95 4. First-aid measures General Advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Eye Contact In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Occupational safety and health guidelines for chemical hazards. suppl. 2, Publisher U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, The lack of pertinent subchronlc oral toxldty data precludes the derivation of an AIS for subchronlc exposure to o- m- and p-cresol.

Inhalation. At an exposure level of 9 mg o-cresol/m3, 6 hours/ day, 5 days/week for 2 months and then for 4 hours/day, 5 days/week for 2 subsequent months, exposed guinea pigs had unspecified changes 1n.

Cresol (C 7 H 8 O), any of the three methylphenols with the same molecular formula but having different structures: ortho- (o-) cresol, meta- (m-) cresol, and para- (p-) cresol. The cresols are obtained from coal tar or petroleum, usually as a mixture of the three stereoisomers (molecules with the same number and type of atoms but with unique atom arrangements).

transitional cell carcinoma of the bladder following chronic occupational exposure to cresol and creosote. Wodyka (, as cited in U.S. EPA., ) described a squamous cell carcinoma of the vocal cords in a petroleum refinery worker with a long history of exposure to cresol, dichlorooctane, and chromic Size: KB.

Clinical relevance Cresol and phenol are formed as metabolites in the body after exposure to toluene and benzene respectively. Toluene and benzene are toxic substances which are used on an industrial scale e.g. as solvents and fuel additives. In 62 male rotogravure printers, the time-weighted average (TWA) toluene exposure during one workweek ranged from 8 to mg/m3 (median 96).

Post-shift urinary excretion of hippuric acid showed a poor correlation with the air toluene concentration. Level of o-cresol excretion ranged from to mmol/mol creatinine and was associated with the Cited by: ortho-Cresol, also 2-methylphenol, is an organic compound with the formula CH 3 C 6 H 4 (OH).

It is a colourless solid that is widely used intermediate in the production of other chemicals. It is a derivative of phenol and is an isomer of p-cresol and ein Reference:   Occupational exposure to 1-bromopropane occurs primarily from its use in spray adhesives, dry cleaning (including use as a spot cleaner), and degreasing (vapor, cold, and aerosol cleaning).

Workers are expected to be the most highly exposed population. Occupational exposure to 1-bromopropane may also occur through skin contact, although. Para-occupational Asbestos Exposure — The Subtle Killer The most common way through which people have been exposed to hazardous levels of asbestos dust is occupational exposure.

Prior to regulation that was enacted in the early s, asbestos and asbestos-laden materials were routinely used throughout a variety of industries for a number of. In this study, health risks of occupational exposure to eight hazardous VOCs (phenol, p-cresol, o/m-cresol, benzene, toluene, ethylbenzene, o-xylene, and m/p-xylene) that are most likely to be emitted from swine buildings were assessed using Monte Carlo simulation.

The purpose of the study was to calculate emission rates and to quantify cancer Cited by: 6.Dietary Exposure Since m-cresol and xylenol are applied only to the bases of fruit and nut trees, no residues are expected to remain in food or feed commodities.

The Agency is requesting the registrant seek an exemption from tolerance (enforceable residue limit). Occupational and Residential Exposure.Seven men came under observation who had been employed between 18 months and three years in a motor-car factory manipulating a mixture of cresol, formol, ammonia and asbestos.

All complained of headache, especially on commencing work, and nausea associated with vomiting. Examination disclosed low blood pressures and tremor.

While the condition was mild, it was Author: M. Duvoir, R. Hazemann, H. Desoille, P. Fallot.